DriverMP

Note: users only need to provide formatted somatic mutation data and tumor&normal gene expression data of a cancer type. The current version of DriverMP provides the HumanNet and STRINGv10 PPI networks (the latter network is about ten times larger than the former).

Data Format Requirements:
A. Mutation Data:

  • (1) Gene IDs should be represented by official symbols, such as CDC25A, CDC25B, ...
  • (2) The first row and column respectively represent the IDs of samples and Genes, and the values (1 or 0) indicate whether the genes are mutated or not on corresponding samples.
  • B. Tumor&Normal Gene Expression Data
  • (1) Gene IDs should be represented by official symbols, such as CDC25A, CDC25B, ...
  • (2) The first row and column respectively represent the IDs of samples and Genes;
  • (3) The gene expression values are recommended to be measured by FPKM;
  • (4) Both the tumor and normal gene expression data with the same format are needed.
  • An example of the needed input data is available below:
            Download DriverMP_example data

    This work is openly licensed via CC0 1.0



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